i 0.50 Hours

Course Overview

This continuing education course evaluates the drug combination known as the “The Holy Trinity,” which consists of an opioid, a benzodiazepine, and a muscle relaxant. The synergistic activity of these drugs may potentiate adverse events and even lead to death. In combination, these drugs can induce side effects such as drowsiness, confusion, tremors, increased seizure risk, and respiratory depression, leading to death. “The Holy Trinity” also has been shown to bring about euphoria in patients, thus creating a potential for drug abuse and misuse.  Pharmacists are frontline professionals who can advise patients on such drug interactions, provide the most appropriate therapy, and deter misuse or abuse.

About the Course Author

Dr. Kazmi is a licensed pharmacist in six states and has practiced community pharmacy for more than a decade. She is a doctor of pharmacy graduate of Philadelphia College of Pharmacy, University of the Sciences. Her pharmacy experience includes medication therapy management, pharmacy operations, managed care, consulting in assisted living facilities, fraud, waste and abuse investigations, and serving as the compliance pharmacist for a state-administered Medicaid pharmacy program. Seema Z. Kazmi, PharmD has declared that no conflict of interest, Relevant Financial Relationship or Relevant Non-Financial Relationship exists.

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Accreditation Information

Certificates provided by accrediting body (1 Match)

  • Accreditation Council for Pharmacy Education


    In support of improving patient care, Relias LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    Type Activity: Knowledge
    Target Audience Designation: P
    ACPE Universal Activity Number: JA4008266-0000-21-268-H05-P

Course Details
  • Course Code:

  • Hours:

  • Type:

    Online Course
  • Release Date:

  • Expiration Date:

  • Learning Objectives:

    Describe the potential adverse effects and pharmacology behind the “The Holy Trinity”.; "Evaluate a patient’s medication profile using the Prescription Drug Monitoring Program for agents in the “The Holy Trinity""."; Identify patients at risk for receiving a “Holy Trinity” prescription.; Recognize the impact of pharmacist intervention on “The Holy Trinity,” specifically prevention.
  • Target Audience:

    The target audience for this course is: Pharmacists; in the following settings: Acute Care Facility.
  • Course Delivery Method and Format:

    Asynchronous/Online Distance Learning; please see certificate details for specifics on delivery format.
    Relias has a grievance policy in place to facilitate reports of dissatisfaction. Relias will make every effort to resolve each grievance in a mutually satisfactory manner. In order to report a complaint or grievance please contact Relias.
    If you require special accommodations to complete this module, please contact Relias Support by completing the web form (https://www.relias.com/help) or by using the chat functionality.
    All courses offered by Relias, LLC are developed from a foundation of diversity, inclusiveness, and a multicultural perspective. Knowledge, values and awareness related to cultural competency are infused throughout the course content.
    Reference herein to any specific commercial product, process, or service by trade name, trademark, service mark, manufacturer or otherwise does not constitute or imply any endorsement, recommendation, or favoring of, or affiliation with, Relias, LLC.
    All characteristics and organizations referenced in the following training are fictional. Any resemblance to any actual organizations or persons living or dead, is purely coincidental.
    To earn continuing education credit for this course you must achieve a passing score of 80% on the post-test and complete the course evaluation.
  • Accommodations:

    If you require special accommodations to complete this module, please contact Relias Customer Support here.
  • Disclosures:

    Expert Reviewers, Instructors, and Staff Writers disclosures will be listed above after the individuals' biographical paragraph. All other members involved within the planning of this educational activity have declared no conflict of interest exists when planning and developing this course.