Toxic Alert - PT500

Toxic Alert

Many Common Drugs Can Damage Kidney and Liver

by Steven S. Bhimji, MD, PhD
(4.4 / 73 ratings )

This course is credentialed for:
Physical Therapy (1.00 Hour(s))

Price: $19.00
CE-PRO Price: $9.50


Although often assumed safe, prescription and OTC medications can cause serious adverse reactions, especially in certain high-risk populations. Acetaminophen (Tylenol) and aspirin are associated with an increased risk of chronic renal failure. These drugs, as well as ibuprofen, are ingredients in many OTC and prescription medications. In addition, with the increase in popularity of complementary medicine, herbal therapy toxicities occur at an accelerated rate. Specifically, OTC drugs, prescription drugs and even herbal products can target the kidney and liver. The causes of these reactions and toxicities are complex, and certain patient populations are more susceptible. Because these reactions are preventable when users are educated about the risks and screened for risk factors before therapy, healthcare providers across disciplines must be able to identify the drugs and their potential toxicities to ensure patient safety.


The goal of this module is to inform nurses, pharmacists, dietitians, EMTs and paramedics, fitness professionals, health educators, imaging and radiation therapists, physical therapists, and physicians about the common OTC, prescription and herbal products that cause renal and liver toxicity, with an emphasis on patient populations at risk. After studying the information presented here, you will be able to:
  • Discuss the drugs that cause renal toxicity and list their mechanisms of toxicity
  • Discuss the drugs that cause liver toxicity and list their mechanisms of toxicity
  • Identify risk factors for the development of drug-induced renal or liver toxicity

Accreditation Information
This course is intended for multiple professions, including nurses, pharmacists, dietitians, EMTs and paramedics, fitness professionals, health educators, imaging and radiation therapists, physical therapists, and physicians.
Physical therapists: Take this version of the course to ensure you receive appropriate credit.
For the version accredited or approved for another profession, go to your specific profession at or If you have a CE Direct login ID and password (generally provided by your employer), please log in as you normally would at and search for this topic title.
OnCourse Learning is an approved sponsor by the New York State Education Department of continuing education for physical therapists and physical therapist assistants from 10/21/09 to 10/20/18.
This activity is provided by the TX Board of PT Examiners Accredited Provider GED012010TPTA2012004 for 01/01/2010 to 01/31/2013; 1601004 for 02/01/2013 to 01/31/2016; and 1902004TX for 02/01/2016 to 01/31/2019 and meets continuing competence requirements for physical therapist and physical therapist assistant licensure renewal in Texas. The assignment of Texas PT CCUs does not imply endorsement of specific course content, products, or clinical procedures by TPTA or TBPTE.
OnCourse Learning is recognized by the Physical Therapy Board of California as an approved reviewer and provider of continuing competency courses for the state of California.
OnCourse Learning is a licensed physical therapy continuing education sponsor (#216.000275) with the Illinois Department of Financial and Professional Regulation from July 2013 through September 30, 2018.
This course has been approved as meeting the continuing education requirements for PTs and PTAs by the Ohio Physical Therapy Association (approval no. 13S1690 for 07/23/13 to 07/23/14; 14S1238 for 07/24/14 to 07/24/15; 15S1563 for 07/25/15 to 07/25/16; 16S1783 for 07/26/16 to 07/26/17); the Florida Physical Therapy Association (approval no. CE130021164 for 01/01/13 to 12/31/13; CE140021379 for 01/01/14 to 12/31/14; CE150024019 for 01/01/15 to 12/31/15; CE16-26865 for 01/01/16 to 12/31/16; CE17-404738 for 01/01/17 to 12/31/17); the Tennessee Physical Therapy Association for Class 1 Continuing Education Requirement (approval no. 5168 for 07/19/13 to 07/18/14; 5661 for 07/19/14 to 07/18/15; 6256 for 07/19/15 to 07/18/16; 2016-216 for 07/19/16 to 07/18/17; 2017-251 for 07/19/17 to 07/18/18); the Pennsylvania Board of Physical Therapy (approval no. PTCE007322 for 01/01/15 to 12/31/16; PTCE010081 for 01/01/17 to 12/31/18) and the New Jersey Board of Physical Therapy Examiners (approval no. 1408-2012 for 08/27/13 to 01/31/14; 729-2014 for 02/01/14 to 01/31/16; 2016-941 for 02/01/16 to 01/31/18). Approval of this course does not necessarily imply the Florida Physical Therapy Association supports the views of the presenter or the sponsors.
This course has been approved by the Nevada State Board of Physical Therapy Examiners for 0.1 units of continuing education for 08/30/13 to 07/31/15; 07/31/15 to 07/31/17.
The Illinois Chapter Continuing Education Committee has certified that this course meets the criteria for approval of Continuing Education offerings established by The Illinois Physical Therapy Association (approval no. 437-4979 for 07/01/13 to 07/01/14). According to the Rules for the Administration of the Illinois Physical Therapy Act (section 13460.61) published by the Illinois Department of Professional Regulation, a physical therapist or physical therapist assistant applying for re-licensure in Illinois can earn a maximum of 50 percent of their required continuing education hours from self-study. The hours awarded of this course are designated for self-study CE credit.
Other states may accept this course for meeting their CE requirements. Check with your state association or board.

Course Originally Released on: 10/7/2002
Date of Most Recent Review: 10/9/2014
Course Termination/Update Date: 10/9/2017


Unless stated above, the planners and authors of this course have declared no relevant conflicts of interest that relate to this educational activity. OnCourse Learning guarantees this educational activity is free from bias.

Please see CE Course Instructions to learn how to earn CE credit for this module.


For Florida professionals:

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Patricia K - shoemakersville, PA  ·  Jul 20, 2017
This course was tough but good. I did not know a lot of this information, so I found it very helpful.
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Rolando H - Orwigsburg , PA  ·  Jul 18, 2017
Appropriate for my current practice setting.
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Colleen I - saugus, CA  ·  Apr 29, 2017
More specific for pharmacist or MD. But good info.
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JACQUELIN P - Memphis, TN  ·  Feb 14, 2017
this course was very informative
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JUDITH G - WARMINSTER, PA  ·  Dec 26, 2016
This course was very useful.
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Price: $19.00
CE-PRO Price: $9.50