The ABO and Rh Blood Groups - 384-012-19

The ABO and Rh Blood Groups

by Michelle Controneo, PhD, MT(ASCP)
(4.6 / 195 ratings )

This course is credentialed for:
Laboratory (1.00 Contact Hr)

Price: $10.00
CE-PRO Price: $5.00


The ABO blood group antigens are expressed on the surface of red blood cells and other cell types. These antigens can cause lethal transfusion reactions in patients receiving incompatible blood products. Accurate blood type determination by forward and reverse grouping as well as cross matching must be performed carefully to ensure compatibility for ABO and D antigens. Prenatal screening should be done to prevent hemolytic disease of the newborn in Rh-negative mothers having Rh-incompatible fetuses.


The goal of this ABO blood group continuing education module is to provide laboratory personnel with the ability to recognize and define the ABO blood groups, to describe the testing involved in their identification, and to demonstrate the procedures involved in forward and reverse testing. After studying the information here, you will be able to:
  • Identify the basic biochemical structure of ABO and D blood group antigens, and the basic process of how enzymes control the synthesis of the ABO antigens
  • Describe how the antigenic expression of ABO and D blood groups is controlled by genes
  • Relate ABO genotypes to their corresponding phenotypes
  • Discuss how rare and acquired phenotypes arise, and how they are handled
  • Know the characteristics of antibodies to ABO and D blood group antigens and their clinical significance
  • Discuss how hemolytic disease of the newborn develops and how it can be prevented
  • Demonstrate the procedures for forward and reverse typing
Level of Instruction: Basic

Approval Information
This course is intended for laboratory professionals.
Relias LLC is approved as a provider of continuing education programs in the clinical laboratory sciences by the American Society for Clinical Laboratory Science (ASCLS) Professional Acknowledgment for Continuing Education (P.A.C.E.®) Program (provider #384).
384-012-19 "The ABO and Rh Blood Groups" is approved 01/31/19 to 01/31/2021.
OnCourse Learning is also approved by the Florida Board of Clinical Laboratory Personnel (provider # 50-1489).

Course Originally Released on: 8/18/2017
Date of Most Recent Review: 8/18/2017
Course Termination/Update Date: 1/31/2021

Unless stated above, the planners and authors of this course have declared no relevant conflicts of interest that relate to this educational activity. Relias LLC guarantees this educational activity is free from bias.

Please see CE Course Instructions to learn how to earn CE credit for this module.


For Florida professionals:

This course completion will be electronically reported to CE Broker as required per Florida Statute 456.025(7). Click here to view your CE Broker transcript and check the status of your CE requirements with a FREE 7-day CE Broker trial subscription. It may take up to 24 hours for the course to appear on your CE Broker transcript.

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Reports to CE Broker

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Erica R - Antioch , CA  ·  Sep 16, 2019
good course will do again
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Evelyn B - Union City, CA  ·  Sep 13, 2019
good material to read
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Jonathan P - Boise, ID  ·  Sep 03, 2019
I was assigned this course by lab manager. I would not have chosen to take this course otherwise.
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Alma Y - Vacaville, CA  ·  Sep 02, 2019
well presented and added to my knowledge
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Nancy J - Boise, ID  ·  Aug 27, 2019
Interesting information about the sugars and chemical differences in the blood types.
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Price: $10.00
CE-PRO Price: $5.00